Vitamins May Help Women Live Longer
Multivitamins may help women live longer by preventing parts of their DNA from shortening. Researchers speculated that preventing this shortening could protect new cells and thus reduce the effects of aging.
“This study provides the first epidemiological evidence that multivitamin use is associated with longer leukocyte telomeres among women,” said lead researcher Dr. Honglei Chen, head of the Aging & Neuroepidemiology Group. “It is not yet clear if this association is causal.”
The report appears in the June issue of the American Journal of Clinical Nutrition. For the study, Chen’s team analyzed data on 586 women participating in the Sisters Study, which included women who had breast cancer and their cancer-free siblings. As part of that study, the women were asked about their use of vitamin supplements over a 12-year span. The researchers also took blood samples and tested DNA.
“We found that multivitamin use was associated with longer leukocyte telomeres,” Chen said. “Compared with nonusers, daily multivitamin users had, on average, 5.1 percent longer leukocyte telomeres.”
This corresponds to about 9.8 years less age-related telomere shortening, the researchers noted. Vitamins C and E from diet also were associated with longer telomeres, Chen said. But, whether the vitamins preserved telomere length or actually lengthened life is not clear, Chen said.
“We could not exclude the possibility that the association could be explained by a healthy lifestyle,” he said. “Although shorter telomere length has been linked to higher mortality and higher risk of chronic diseases, it is premature to conclude that multivitamin use is associated with slower aging process.”
Dr. David Katz, director of the Prevention Research Center at Yale University School of Medicine, thinks there are mixed messages about the value of taking vitamins, and until there is some definitive science on the issue, taking them is a personal decision.
“Most recent studies of vitamin supplements have yielded discouraging results,” Katz said. “This study clearly goes the other way, suggesting that a multivitamin may help protect our chromosomes, and thus ourselves, from aging.”